SP255DRUG DOSING IN CHRONIC KIDNEY DISEASE: IS THE COCKCROFT-GAULT FORMULA ALWAYS THE BEST ESTIMATOR OF RENAL FUNCTION TO PREVENT OVEREXPOSURE?

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Should we continue to use the Cockcroft-Gault formula?

BACKGROUND/AIMS Although the National Kidney Disease Education Program recommends use of the modification of diet in renal disease (MDRD) formula to estimate the glomerular filtration rate (GFR), most drug-dosing recommendations and clinical practices employ the Cockcroft-Gault (CG) formula. The quality score of the original MDRD study was better than that of the original CG study, although the...

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Should We Continue to Use the Cockcroft-Gault Formula?

Background/Aims: Although the National Kidney Disease Education Program recommends use of the modification of diet in renal disease (MDRD) formula to estimate the glomerular filtration rate (GFR), most drug-dosing recommendations and clinical practices employ the Cockcroft-Gault (CG) formula. The quality score of the original MDRD study was better than that of the original CG study, although th...

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Predictive performance of the modification of diet in renal disease and Cockcroft-Gault equations for estimating renal function.

Recent recommendations emphasize the need to assess kidney function using creatinine-based predictive equations to optimize the care of patients with chronic kidney disease. The most widely used equations are the Cockcroft-Gault (CG) and the simplified Modification of Diet in Renal Disease (MDRD) formulas. However, they still need to be validated in large samples of subjects, including large no...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2016

ISSN: 1460-2385,0931-0509

DOI: 10.1093/ndt/gfw163.36